Pharmacology of the endocrine system 2 in clinical practice, hormones and hormonelike drugs, are mainly used for. Alcohols effects on male reproduction mary ann emanuele, m. Currently, the most consistent evidences of a detrimental effect of smoke, alcohol and addictive drugs on specific domains of the female reproductive function are provided by experimental studies in animals. It effectively makes you menopausal for the short time that you use the treatment and without the oestrogen stimulation, endometriosis shrinks down and. More in bone, reproductive and urologic drugs advisory committee.
Genitourinary tract agents are medicines, which are used to treat conditions of the reproductive organs and excretory system or urinary tract. The cpap mask fits snugly over the patients nose and the oxygen is delivered via a short hose connected to the cpap machine. Unfortunately compliance using these devices is limited by the wearers discomfort due to the. For example, a toxicant might mimic the action of naturally occurring reproductive hormones. The health risk depends on how much exposure a worker has to these drugs. Gonadotropinreleasing hormone gnrh and its analogues are used for treatment of ovarian cysts and for control of ovarian follicular dynamics in cattle, for estrus induction by pulsatile administration in mares and bitches, and for stimulation of testicular. Cetrorelix inhibits premature lh surges in women undergoing controlled overain stimulation by acting as a gnrh antagonist.
The nervous system controls all the major functions of the body. The female reproductive system works in a cyclical fashion and altering the components of this cycle can have a variety of effects to the body. Consider the thyroid gland, an important part of this system. However, directly acting drugs are more important and. If your institution subscribes to this resource, and you dont have a myaccess profile, please contact your librarys reference desk for information on how to gain access to this resource from offcampus.
While research on the endocrinological effect of illicit drugs on the reproductive system is still in its infancy, this paper seeks to justify that. Drugs acting on urogenital system animals pharmacology. Risks for success and breast cancer depend on the individual circumstances, so this would not be appropriate teaching. Persons with disabilities having problems accessing the pdf files may call 301 7963634 for assistance.
Brown encyclopedia of life support systems eolss reproductive pharmacology jocelyn n. Toxicity of nanoparticles on the reproductive system in animal models. Guidelines and essential drugs list for primary health care the green book were. Reproductive risks of drug abuse the degree of reproductive risks from drug abuse depends on many factors.
The endocrinological effect of illicit drugs on the. Male or female reproductive health may be retarded depending upon stage of metal exposure such as the prenatal, prematurity, or maturity stage as well as the route, dose, and duration of exposure, the evidence of which is generally animal data driven. Drugs acting on respiratory system animals pharmacology. Bone, reproductive and urologic drugs advisory committee. Pharmacology of drugs acting on uterus mbbs childbirth. Toxicity of nanoparticles on the reproductive system in.
The effects of cancer treatment on reproductive functions. Find specific details on this topic and related topics from the merck vet manual. The nurse is caring for a female patient who would like to start taking oral contraceptives. This chapter describes a number of pharmacological agents used to treat respiratory disease in the critically ill. Stds and other infections drug and alcohol abuse may put men at higher risk of contracting stds. Antimuscarinic drugs for urinary frequency, urgency, and incontinence overactive bladder syndrome. Hormones and hormonallike agents are primarily the drugs that affect the female reproductive system. Drugs acting on the immune system pharmacology education. Drugs acting on the endocrine system thyroid glands. Introduction endocrine system glands groups of cells that secrete regulatory substances directly into blood stream regulatory substances diffuse across cell membranes one of two major control mechanisms for the body the other is the nervous system linked closely with the nervous system. Smoke, alcohol and drug addiction and female fertility.
Drug addiction, including an addiction to opioids, is a disability under section 504 of the rehabilitation act, the americans with disabilities act, and section 1557 of the affordable care act, when the drug. Although not approved for use in the uk, zileuton is approved in the us for the maintenance treatment of asthma. Drugs acting in cns were among the first to be discovered by primitive humans and are still the most widely used group of pharmacologic agents. Pain medications and male reproduction request pdf.
Drugs acting upon the central nervous system last updated. Request pdf pain medications and male reproduction the increasing use of opioid. Learn vocabulary, terms, and more with flashcards, games, and other study tools. The male reproductive system consists of the hypothalamus, the anterior pituitary gland, and the testes.
Drugs affecting the male reproductive system include androgens male steroid hormones, anabolic steroids, and drugs that improve penile dysfunction. Alcohol can interfere with the function of each of these components, thereby. The peripheral nervous system receives thousands of sensory inputs and transmits them to the brain via the spinal cord. There are several sites of action where reproductive toxicants can act and alter the normal function of hypothalamus, anterior pituitary, ovary, uterus, vagina, or mammary gland. Tocolytic therapy betasympathomimetic drugs act by stimulating beta2 receptors of smooth muscles. Male sexual activity is dependent on the dopaminergic system.
Stillbirth pregnancy, highrisk see health problems in pregnancy. These drugs are used to enhance mental alertness and reduce drowsiness and fatigue. Semen is a mixture of sperm and fluid from the male reproductive organs. Drugs acting on the immune system the immune system discriminates self from nonself allowing it to destroy infectious invaders or tumors while leaving normal cells intact. Male reproductive system hormonal function and regulation sperm synthesis and maturation duration.
Many drugs have either primary or secondary effects on the cardiovascular and autonomic nervous systems. Jun 07, 2019 the female reproductive system works in a cyclical fashion and altering the components of this cycle can have a variety of effects to the body. Office of chemical safety, department of health and ageing, woden, act 2606. Drugs acting on eye, respiratory system and miscellaneous drugs. Drugs acting on the endocrine system is the property of its rightful owner. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.
Overview of systemic pharmacotherapeutics of the reproductive. Pde5 receptor inhibitors act to increase nitrous oxide levels in the corpus cavernosum. Penis contains tissue that fills with blood during sexual arousal, making the penis erect or hard. This may be due to lowered inhibitions associated with substance use. Pennefather department of pharmaceutical biology, victorian college of pharmacy, monash university, parkville, vic 3052, australia. They include medicines used for bladder spasms, urinary ph modifiers, medicines for erectile dysfunction in men and medicines that suppress uterine contractions to prevent preterm labor. Yo u notice that some students changed a lot over the summer. Articles in languages other than english were excluded. Reproductive pharmacology is a vast topic with applications in all aspects.
Drugs acting on the cardiovascular system clinical gate. Discuss the microorganisms that infect the urinary and reproductive system. Autonomic nervous system drugs william mark enlow sue greenfield cliff roberson keyt erm s acetchnyoll ei ne achi ceyoel tral tsse adrenalmedulla adenr ercaggi on sts i adrenergc i antagon sist adrenergcnevi er s adenr erecceprgi ort s auonomt cneri vou s ystes man s cardiosve ei cetl ceacthamol ine. Realworld reading connection its the first day of school. Nitrous oxide activates the enzyme cyclic guanosine monophosphate cgmp to cause smooth muscle relaxation and increased flow of blood. Ppt drugs acting on the endocrine system powerpoint.
Myometrium receives both sympathetic and parasympathetic innervation. Drug abuse and reproduction fertility and sterility. Endocrine and reproductive pharmacology authorstream presentation. Female reproductive toxicity an overview sciencedirect. Testing the functional integration of an endocrine system diagnostic. This is particularly true of the attempted control of mastitis by the repeated application of intramammary agents containing one or other of the indicated drugs. Oxytocinpitocin indicated for the initiation or improvement of uterine contractions, where this is desirable and considered suitable for reasons of fetal or maternal concern, in order to achieve vaginal delivery. Psychic stimulants include caffeine, cocaine, and various amphetamines. The most important drugs affecting endometrium are estrogens and progestins. Gonadotropins are drugs that act similarly to gnrh, lh, or fsh. Drugs acting on reproductive system by, dr saima mahmood malhi assistant professor 1. Estradiol initially activates the circuit by acting in the.
Chapter 40 drugs affecting the female reproductive system my. Additional articles were retrieved from references list of selected manuscripts. Some of these drugs are used for the explicit purpose of affecting an endocrine process, while still others affect a hormonal action, usually as. Genitourinary system pharmacology education project. Drugs acting on gastrointestinal tract authorstream. These drugs have a bronchodilator action of 12 hours and also protect against bronchoconstriction for a similar period.
Drugs used in disorders of the reproductive system slideshare. Chapter 40 drugs affecting the female reproductive system. A drug acting on the same inflammatory pathway is zileuton, which inhibits the 5lox 5lipoxygenase enzyme that catalyses the formation of leukotrienes ltb 4, ltc 4, ltd 4, and lte 4 from arachidonic acid. Drugs acting on the respiratory system springerlink. List and describe the pharmacology of various drugs acting on the urinary and reproductive system. In addition to their use in therapy, many drugs acting on the cns are used without prescription to increase ones sense of well being.
Drugs used to regulate or control the reproductive system are often naturally occurring hormones or chemical modifications of hormones. Several of the drugs discussed in this chapter have more than one clinical indication and the drugs are considered according to their mechanism of action. It would be important to know the drug prescribed before knowing if there was a chance for breakthrough bleeding. Chapter 40 drugs affecting the female reproductive system my nursing test banks 1. Drugs acting on uterus can primarily affect the endometrium or myometrium.
Drugs used to treat kidney and urinary tract disorders. These are often used to induce or suppress estrus, the time during the reproductive cycle in animals when the female displays interest in mating, often called heat. Drugs used to treat reproductive disorders special pet topics. The central nervous system directs the functions of all tissues of the body. The mechanisms of female reproductive toxicity vary.
Drugs used to regulate and control the reproductive system are often naturally occurring hormones or chemical modifications of hormones. The peripheral nervous system includes the somatic and autonomic nervous systems which control voluntary and involuntary functions respectively. They tend to have very long halflives of days to weeks, metabolism is not. At lower doses, alcohol can act as a stimulant,3 inducing feelings of euphoria and talkativeness, but drinking too much alcohol at one session can lead to drowsiness, respiratory depression where breathing becomes slow, shallow or stops entirely. Feb 27, 2007 persons with disabilities having problems accessing the pdf files may call 301 7963634 for assistance.
Start studying drugs acting on the reproductive system. Drugs used to treat reproductive disorders veterinary manual. Oct 04, 2016 this feature is not available right now. Drugs affecting the endocrine system lange smart charts. Reproductive pharmacology encyclopedia of life support.
Steroid hormones penetrate the cell membrane and interact with receptors on specific binding proteins, which then act on the cell nucleus to modify protein. The body normally makes gnrh in a small gland in the brain the pituitary and it is this hormone that stimulates the ovary to develop eggs and produce oestrogen, leading to the normal menstrual cycle. Chapter 39 introduction to the reproductive system. Stimulants are drugs that exert their action through excitation of the central nervous system. Drugs used to treat urinary disorders include antibiotics and antifungal medications for infections, diuretics for kidney failure, and a variety of other drugs for several other disorders. Chapter 54 drugs acting on the upper respiratory tract. The longacting inhaled beta2 agonists laba salmeterol, formoterol, and arformoterol have proved to be a significant advance in asthma and copd therapy.
These struggles can damage many systems in the body, including the reproductive system. Pregnancy hazards see reproductive hazards pregnancy loss see miscarriage. On the other hand, drugs without inherent hormonal activity are able to affect particular target organs of the endocrine system. Female reproductive system drugs nursing pharmacology. The menstrual cycle and drugs used in menstrual disorders and the menopause. Pharmacology of drugs acting on uterus mbbs free download as powerpoint presentation. Are the drugs which increase respiratory secretions or sputum volume and reduce the viscosity of sputum. Pdf beside cytotoxic drugs, other drugs can impact mens fertility through various mechanisms. Effects of drugs on the endocrine system springerlink. Mar 29, 2016 drugs acting on respiratory system slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Men may experience one or more of the following reproductive problems as a result of drug and alcohol use.
Darifenacin, fesoterodine antimuscarinic prodrug, flavoxate also used for bladder spasms due to catheterisation, cytoscopy, or surgery, hyoscine scopolamine butylbromide for symptomatic relief of gastrointestinal or genitourinary disorders characterised by smooth muscle spasm, oxybutynin. The wide application of nanomaterials in industry, consumer products, and medicine has raised concerns regarding the potential toxicity of nanoparticles in humans. Changing to short acting agents just prior to drug testing. If you continue browsing the site, you agree to the use of cookies on this website. The treatment of cattle by homeopathy macleod, george.
Drugs acting upon the central nervous system chemistry. Drugs acting on the endocrine system by kathrine kaye. Male reproductive health an overview sciencedirect topics. Gonadotropins cause the release of lh and fsh or cause activity similar to that of lh or fsh. Drugs used in hormonal, endocrine, and reproductive disorders.
Learn about the veterinary topic of drugs used to treat kidney and urinary tract disorders. Drugs acting on respiratory system slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. A more intrusive delivery system is the continuous positive airway pressure cpap device, often used to treat sleep apnea. Endocrine and reproductive pharmacology authorstream. Jun 01, 2009 uterotropic drugs enhance uterine contractility by stimulating the smooth muscle of the uterus. Understand the pathogenesis of various diseases of the urinary and reproductive system. While some people can take a substance without developing cravings, compulsion, or addiction, many of the people who used substances in the survey were at risk of becoming addicted to drugs or alcohol. The male reproductive system the male reproductive organs are the penis, the testicles, the epididymis, the vas deferens and the prostate gland. After reading this article you will learn about the various drugs acting on respiratory system. Drugs used in disorders of the reproductive system. Drugs acting on the autonomic nervous system yaaka. Two components, innate and adaptive provide an early active response and an antigenspecific response, respectively. Oct 04, 2016 reproductive system drugs medical assistant.
It includes respiratory stimulants, bronchodilators, corticosteroids, magnesium, pulmonary vasodilators and mucolytic agents. Drug addiction and federal disability rights laws fact sheet. Focus on nursing pharmacology karch edition 6 nursing. If so, share your ppt presentation slides online with.
If you give gnrh agonists, this floods the system and confuses the delicately controlled balance, leading to a complete block of egg development, oestrogen production and menstrual cycle. There are many drugs that can be used to influence the endocrine system. Learn about the veterinary topic of drugs acting on the blood or bloodforming organs. Male reproductive system drugs nursing pharmacology guide. It is divided into central and peripheral nervous systems. Drugs acting on reproductive system by, dr saima mahmood malhi assistant professor 1 introduction. Essential medicines reproductive health world health organization. Drugs acting on the endocrine system hypothalamic and pituitary agents pharmacokinetics for the most part, these drugs are absorbed slowly when given intramuscularly im, subcutaneously, or in depot form. Drugs acting on the reproductive system flashcards quizlet. Advisory committees drugs bone, reproductive and urologic drugs advisory committee formerly reproductive health drugs advisory committee.
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